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Bordetella adenylate cyclase toxin is a unique ligand of the integrin complement receptor 3

Integrins are heterodimeric cell surface adhesion and signaling receptors that are essential for metazoan existence. Some integrins contain an I-domain that is a major ligand binding site. The ligands preferentially engage the active forms of the integrins and trigger signaling cascades that alter n...

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Publicado en:eLife
Autores principales: Osicka, Radim, Osickova, Adriana, Hasan, Shakir, Bumba, Ladislav, Cerny, Jiri, Sebo, Peter
Formato: Artigo
Lenguaje:Inglês
Publicado: eLife Sciences Publications, Ltd 2015
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4755762/
https://ncbi.nlm.nih.gov/pubmed/26650353
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.10766
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