Bordetella Pertussis Adenylate Cyclase Toxin Does Not Possess a Phospholipase A Activity; Serine 606 and Aspartate 1079 Residues Are Not Involved in Target Cell Delivery of the Ade...

by Bumba, Ladislav, Masin, Jiri, Osickova, Adriana, Osicka, Radim, Sebo, Peter
Published in Toxins (Basel) (2018)

Bordetella adenylate cyclase toxin is a unique ligand of the integrin complement receptor 3

by Osicka, Radim, Osickova, Adriana, Hasan, Shakir, Bumba, Ladislav, Cerny, Jiri, Sebo, Peter
Published in eLife (2015)

Rapid Purification of Endotoxin-Free RTX Toxins

by Stanek, Ondrej, Masin, Jiri, Osicka, Radim, Jurnecka, David, Osickova, Adriana, Sebo, Peter
Published in Toxins (Basel) (2019)

Binding of Kingella kingae RtxA Toxin Depends on Cell Surface Oligosaccharides, but Not on β(2) Integrins

by Rahman, Waheed Ur, Osickova, Adriana, Klimova, Nela, Lora, Jinery, Balashova, Nataliya, Osicka, Radim
Published in Int J Mol Sci (2020)

Delivery of CD8(+) T-Cell Epitopes into Major Histocompatibility Complex Class I Antigen Presentation Pathway by Bordetella pertussis Adenylate Cyclase: Delineation of Cell Invasiv...

by Osička, Radim, Osičková, Adriana, Basar, Tümay, Guermonprez, Pierre, Rojas, Marie, Leclerc, Claude, Šebo, Peter
Published 2000

Retargeting from the CR3 to the LFA-1 receptor uncovers the adenylyl cyclase enzyme–translocating segment of Bordetella adenylate cyclase toxin

by Masin, Jiri, Osickova, Adriana, Jurnecka, David, Klimova, Nela, Khaliq, Humaira, Sebo, Peter, Osicka, Radim
Published in J Biol Chem (2020)

The conserved tyrosine residue 940 plays a key structural role in membrane interaction of Bordetella adenylate cyclase toxin

by Masin, Jiri, Roderova, Jana, Osickova, Adriana, Novak, Petr, Bumba, Ladislav, Fiser, Radovan, Sebo, Peter, Osicka, Radim
Published in Sci Rep (2017)

Structure–Function Relationships Underlying the Capacity of Bordetella Adenylate Cyclase Toxin to Disarm Host Phagocytes

by Novak, Jakub, Cerny, Ondrej, Osickova, Adriana, Linhartova, Irena, Masin, Jiri, Bumba, Ladislav, Sebo, Peter, Osicka, Radim
Published in Toxins (Basel) (2017)

Residues 529 to 549 participate in membrane penetration and pore-forming activity of the Bordetella adenylate cyclase toxin

by Roderova, Jana, Osickova, Adriana, Sukova, Anna, Mikusova, Gabriela, Fiser, Radovan, Sebo, Peter, Osicka, Radim, Masin, Jiri
Published in Sci Rep (2019)

Delivery of Multiple Epitopes by Recombinant Detoxified Adenylate Cyclase of Bordetella pertussis Induces Protective Antiviral Immunity

by Fayolle, Catherine, Osickova, Adriana, Osicka, Radim, Henry, Thomas, Rojas, Marie-Jésus, Saron, Marie-Françoise, Sebo, Peter, Leclerc, Claude
Published 2001

Negatively charged residues of the segment linking the enzyme and cytolysin moieties restrict the membrane-permeabilizing capacity of adenylate cyclase toxin

by Masin, Jiri, Osickova, Adriana, Sukova, Anna, Fiser, Radovan, Halada, Petr, Bumba, Ladislav, Linhartova, Irena, Osicka, Radim, Sebo, Peter
Published in Sci Rep (2016)

Acyltransferase-mediated selection of the length of the fatty acyl chain and of the acylation site governs activation of bacterial RTX toxins

by Osickova, Adriana, Khaliq, Humaira, Masin, Jiri, Jurnecka, David, Sukova, Anna, Fiser, Radovan, Holubova, Jana, Stanek, Ondrej, Sebo, Peter, Osicka, Radim
Published in J Biol Chem (2020)

Intrinsically disordered proteins drive enamel formation via an evolutionarily conserved self-assembly motif

by Wald, Tomas, Spoutil, Frantisek, Osickova, Adriana, Prochazkova, Michaela, Benada, Oldrich, Kasparek, Petr, Bumba, Ladislav, Klein, Ophir D., Sedlacek, Radislav, Sebo, Peter, Prochazka, Jan, Osicka, Radim
Published in Proc Natl Acad Sci U S A (2017)

Cytotoxic activity of Kingella kingae RtxA toxin depends on post-translational acylation of lysine residues and cholesterol binding

by Osickova, Adriana, Balashova, Nataliya, Masin, Jiri, Sulc, Miroslav, Roderova, Jana, Wald, Tomas, Brown, Angela C., Koufos, Evan, Chang, En Hyung, Giannakakis, Alexander, Lally, Edward T., Osicka, Radim
Published in Emerg Microbes Infect (2018)

Intrinsically Disordered Enamel Matrix Protein Ameloblastin Forms Ribbon-like Supramolecular Structures via an N-terminal Segment Encoded by Exon 5

by Wald, Tomas, Osickova, Adriana, Sulc, Miroslav, Benada, Oldrich, Semeradtova, Alena, Rezabkova, Lenka, Veverka, Vaclav, Bednarova, Lucie, Maly, Jan, Macek, Pavel, Sebo, Peter, Slaby, Ivan, Vondrasek, Jiri, Osicka, Radim
Published 2013