Host STING-dependent MDSC mobilization drives extrinsic radiation resistance

Radiotherapy induces and promotes innate and adaptive immunity in which host STING plays an important role. However, radioresistance in irradiated tumors can also develop, resulting in relapse. Here we report a mechanism by which extrinsic resistance develops after local ablative radiation that reli...

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Enregistré dans:
Détails bibliographiques
Publié dans:Nat Commun
Auteurs principaux: Liang, Hua, Deng, Liufu, Hou, Yuzhu, Meng, Xiangjiao, Huang, Xiaona, Rao, Enyu, Zheng, Wenxin, Mauceri, Helena, Mack, Matthias, Xu, Meng, Fu, Yang-Xin, Weichselbaum, Ralph R.
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2017
Sujets:
Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5701019/
https://ncbi.nlm.nih.gov/pubmed/29170400
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-01566-5
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