Non-canonical NF-κB Antagonizes STING Sensor-Mediated DNA Sensing in Radiotherapy

The NF-κB pathway plays a crucial role in supporting tumor initiation, progression, and radioresistance of tumor cells. However, the role of the NF-κB pathway in radiation-induced anti-tumor host immunity remains unclear. Here we demonstrated that inhibiting the canonical NF-κB pathway dampened the...

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Publicado no:Immunity
Main Authors: Hou, Yuzhu, Liang, Hua, Rao, Enyu, Zheng, Wenxin, Huang, Xiaona, Deng, Liufu, Zhang, Yuan, Yu, Xinshuang, Xu, Meng, Mauceri, Helena, Arina, Ainhoa, Weichselbaum, Ralph R., Fu, Yang-Xin
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6775781/
https://ncbi.nlm.nih.gov/pubmed/30170810
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2018.07.008
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