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Extrinsic Phagocyte-Dependent STING-Signaling Dictates the Immunogenicity of Dying Cells
The ability of dying cells to activate antigen presenting cells (APCs) is carefully controlled to avoid unwarranted inflammatory responses. Here we show that engulfed cells containing cytosolic dsDNA species (viral or synthetic) or cyclic di-nucleotides (CDNs) are able to stimulate APCs, via extrins...
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| izdano v: | Cancer Cell |
|---|---|
| Main Authors: | , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2018
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6177226/ https://ncbi.nlm.nih.gov/pubmed/29706455 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccell.2018.03.027 |
| Oznake: |
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