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Deregulation of STING Signaling in Colorectal Carcinoma Constrains DNA-Damage Responses and Correlates With Tumorigenesis
STING (stimulator of interferon genes) has been shown to be critical for controlling anti-viral responses, as well as anti-tumor adaptive immunity but little is known regarding its regulation in human tumors. Here, we report that STING-signaling is recurrently suppressed in a wide variety of cancers...
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| Опубликовано в: : | Cell Rep |
|---|---|
| Главные авторы: | , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2015
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4845097/ https://ncbi.nlm.nih.gov/pubmed/26748708 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2015.12.029 |
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