Pharmacokinetics and Tissue Penetration of Ceftolozane-Tazobactam in Diabetic Patients with Lower Limb Infections and Healthy Adult Volunteers

Ceftolozane-tazobactam displays potent activity against Gram-negative bacteria that can cause diabetic foot infections (DFI), making it an attractive treatment option when few alternatives exist. The pharmacokinetics and tissue penetration of ceftolozane-tazobactam at 1.5 g every 8 h (q8h) in patien...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Monogue, Marguerite L., Stainton, Sean M., Baummer-Carr, Arlinda, Shepard, Ashley K., Nugent, James F., Kuti, Joseph L., Nicolau, David P.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2017
Assuntos:
Clinical Therapeutics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5700352/
https://ncbi.nlm.nih.gov/pubmed/28893779
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01449-17
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