Comparative Assessment of Tedizolid Pharmacokinetics and Tissue Penetration between Diabetic Patients with Wound Infections and Healthy Volunteers via In Vivo Microdialysis

Herein, we present pharmacokinetic and tissue penetration data for oral tedizolid in hospitalized patients with diabetic foot infections (DFI) compared with healthy volunteers. Participants received oral tedizolid phosphate 200 mg every 24 h for 3 doses to achieve steady state. A microdialysis cathe...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Stainton, Sean M., Monogue, Marguerite L., Baummer-Carr, Arlinda, Shepard, Ashley K., Nugent, James F., Kuti, Joseph L., Nicolau, David P.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2017
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5740339/
https://ncbi.nlm.nih.gov/pubmed/29109162
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01880-17
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