Tissue Penetration and Pharmacokinetics of Tigecycline in Diabetic Patients with Chronic Wound Infections Described by Using In Vivo Microdialysis

Tissue penetration of systemic antibiotics is an important consideration for positive outcomes in diabetic patients. Herein we describe the exposure profile and penetration of tigecycline in the interstitial fluid of wound margins versus that of uninfected thigh tissue in 8 adult diabetic patients i...

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Detalhes bibliográficos
Main Authors: Bulik, Catharine C., Wiskirchen, Dora E., Shepard, Ashley, Sutherland, Christina A., Kuti, Joseph L., Nicolau, David P.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2010
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2981255/
https://ncbi.nlm.nih.gov/pubmed/20921312
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01051-10
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