Comparative Assessment of Tedizolid Pharmacokinetics and Tissue Penetration between Diabetic Patients with Wound Infections and Healthy Volunteers via In Vivo Microdialysis

Herein, we present pharmacokinetic and tissue penetration data for oral tedizolid in hospitalized patients with diabetic foot infections (DFI) compared with healthy volunteers. Participants received oral tedizolid phosphate 200 mg every 24 h for 3 doses to achieve steady state. A microdialysis cathe...

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Publicado en:Antimicrob Agents Chemother
Autores principales: Stainton, Sean M., Monogue, Marguerite L., Baummer-Carr, Arlinda, Shepard, Ashley K., Nugent, James F., Kuti, Joseph L., Nicolau, David P.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2017
Materias:
Pharmacology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5740339/
https://ncbi.nlm.nih.gov/pubmed/29109162
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01880-17
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