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In Vitro-In Vivo Discordance with Humanized Piperacillin-Tazobactam Exposures against Piperacillin-Tazobactam-Resistant/Pan-β-Lactam-Susceptible Klebsiella pneumoniae Strains

Recent findings have identified Klebsiella pneumoniae strains that are pan-β-lactam susceptible (PBL-S) but piperacillin-tazobactam resistant (TZP-R) in vitro. We assessed the efficacy of a humanized exposure of piperacillin-tazobactam (TZP) against 12 TZP-R/PBL-S K. pneumoniae isolates in an immuno...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Stainton, S. M., Monogue, M. L., Nicolau, D. P.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5487623/
https://ncbi.nlm.nih.gov/pubmed/28607019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00491-17
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