Comparing BMD‐derived genotoxic potency estimations across variants of the transgenic rodent gene mutation assay

There is growing interest in quantitative analysis of in vivo genetic toxicity dose‐response data, and use of point‐of‐departure (PoD) metrics such as the benchmark dose (BMD) for human health risk assessment (HHRA). Currently, multiple transgenic rodent (TGR) assay variants, employing different rod...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Environ Mol Mutagen
Egile Nagusiak: Wills, John W., Johnson, George E., Battaion, Hannah L., Slob, Wout, White, Paul A., Gollapudi, B.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: John Wiley and Sons Inc. 2017
Gaiak:
Research Articles
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5698699/
https://ncbi.nlm.nih.gov/pubmed/28945287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/em.22137
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