Comparing BMD‐derived genotoxic potency estimations across variants of the transgenic rodent gene mutation assay

There is growing interest in quantitative analysis of in vivo genetic toxicity dose‐response data, and use of point‐of‐departure (PoD) metrics such as the benchmark dose (BMD) for human health risk assessment (HHRA). Currently, multiple transgenic rodent (TGR) assay variants, employing different rod...

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Dades bibliogràfiques
Publicat a:Environ Mol Mutagen
Autors principals: Wills, John W., Johnson, George E., Battaion, Hannah L., Slob, Wout, White, Paul A., Gollapudi, B.
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2017
Matèries:
Research Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5698699/
https://ncbi.nlm.nih.gov/pubmed/28945287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/em.22137
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