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Estimating the carcinogenic potency of chemicals from the in vivo micronucleus test

In this study, we investigated the applicability of using in vivo mouse micronucleus (MN) data to derive cancer potency information. We also present a new statistical methodology for correlating estimated potencies between in vivo MN tests and cancer studies, which could similarly be used for other...

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Detalhes bibliográficos
Publicado no:Mutagenesis
Main Authors: Soeteman-Hernández, Lya G., Johnson, George E., Slob, Wout
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5909889/
https://ncbi.nlm.nih.gov/pubmed/26163673
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/mutage/gev043
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