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Comparison of in vitro and in vivo clastogenic potency based on benchmark dose analysis of flow cytometric micronucleus data

The application of flow cytometry as a scoring platform for both in vivo and in vitro micronucleus (MN) studies has enabled the efficient generation of high quality datasets suitable for comprehensive assessment of dose–response. Using this information, it is possible to obtain precise estimates of...

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Detalhes bibliográficos
Publicado no:Mutagenesis
Main Authors: Bemis, Jeffrey C., Wills, John W., Bryce, Steven M., Torous, Dorothea K., Dertinger, Stephen D., Slob, Wout
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6159540/
https://ncbi.nlm.nih.gov/pubmed/26049158
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/mutage/gev041
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