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Comparison of in vitro and in vivo clastogenic potency based on benchmark dose analysis of flow cytometric micronucleus data

The application of flow cytometry as a scoring platform for both in vivo and in vitro micronucleus (MN) studies has enabled the efficient generation of high quality datasets suitable for comprehensive assessment of dose–response. Using this information, it is possible to obtain precise estimates of...

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Vydáno v:Mutagenesis
Hlavní autoři: Bemis, Jeffrey C., Wills, John W., Bryce, Steven M., Torous, Dorothea K., Dertinger, Stephen D., Slob, Wout
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6159540/
https://ncbi.nlm.nih.gov/pubmed/26049158
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/mutage/gev041
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