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Comparison of in vitro and in vivo clastogenic potency based on benchmark dose analysis of flow cytometric micronucleus data

The application of flow cytometry as a scoring platform for both in vivo and in vitro micronucleus (MN) studies has enabled the efficient generation of high quality datasets suitable for comprehensive assessment of dose–response. Using this information, it is possible to obtain precise estimates of...

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Bibliografske podrobnosti
izdano v:Mutagenesis
Main Authors: Bemis, Jeffrey C., Wills, John W., Bryce, Steven M., Torous, Dorothea K., Dertinger, Stephen D., Slob, Wout
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2016
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6159540/
https://ncbi.nlm.nih.gov/pubmed/26049158
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/mutage/gev041
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