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The impact of recombination on human mutation load and disease
Recombination promotes genomic integrity among cells and tissues through double-strand break repair, and is critical for gamete formation and fertility through a strict regulation of the molecular mechanisms associated with proper chromosomal disjunction. In humans, congenital defects and recurrent...
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| Publicat a: | Philos Trans R Soc Lond B Biol Sci |
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| Autors principals: | , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
The Royal Society
2017
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5698626/ https://ncbi.nlm.nih.gov/pubmed/29109227 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rstb.2016.0465 |
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