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The impact of recombination on human mutation load and disease

Recombination promotes genomic integrity among cells and tissues through double-strand break repair, and is critical for gamete formation and fertility through a strict regulation of the molecular mechanisms associated with proper chromosomal disjunction. In humans, congenital defects and recurrent...

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Bibliografske podrobnosti
izdano v:Philos Trans R Soc Lond B Biol Sci
Main Authors: Alves, Isabel, Houle, Armande Ang, Hussin, Julie G., Awadalla, Philip
Format: Artigo
Jezik:Inglês
Izdano: The Royal Society 2017
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5698626/
https://ncbi.nlm.nih.gov/pubmed/29109227
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rstb.2016.0465
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