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Functional modules, mutational load and human genetic disease

The ability to generate a massive amount of sequencing and genotyping data is transforming the study of human genetic disorders. Driven by such innovation, it is likely that whole exome and whole-genome resequencing will replace regionally focused approaches for gene discovery and clinical testing i...

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Detalhes bibliográficos
Main Authors: Zaghloul, Norann A., Katsanis, Nicholas
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3740181/
https://ncbi.nlm.nih.gov/pubmed/20226561
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tig.2010.01.006
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