Discovery and characterization of stable and toxic Tau/phospholipid oligomeric complexes

The microtubule-associated protein Tau plays a central role in the pathogenesis of Alzheimer’s disease. Although Tau interaction with membranes is thought to affect some of its physiological functions and its aggregation properties, the sequence determinants and the structural and functional consequ...

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Bibliografske podrobnosti
izdano v:Nat Commun
Main Authors: Ait-Bouziad, Nadine, Lv, Guohua, Mahul-Mellier, Anne-Laure, Xiao, Shifeng, Zorludemir, Gizem, Eliezer, David, Walz, Thomas, Lashuel, Hilal A.
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2017
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5698329/
https://ncbi.nlm.nih.gov/pubmed/29162800
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-01575-4
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