Fibril growth and seeding capacity play key roles in α-synuclein-mediated apoptotic cell death

The role of extracellular α-synuclein (α-syn) in the initiation and the spreading of neurodegeneration in Parkinson's disease (PD) has been studied extensively over the past 10 years. However, the nature of the α-syn toxic species and the molecular mechanisms by which they may contribute to neu...

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Foilsithe in:Cell Death Differ
Main Authors: Mahul-Mellier, A-L, Vercruysse, F, Maco, B, Ait-Bouziad, N, De Roo, M, Muller, D, Lashuel, H A
Formáid: Artigo
Teanga:Inglês
Foilsithe: Nature Publishing Group 2015
Ábhair:
Original Paper
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4816119/
https://ncbi.nlm.nih.gov/pubmed/26138444
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2015.79
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