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Domain a’ of protein disulfide isomerase plays key role in inhibiting α-synuclein fibril formation
α-Synuclein (αSyn) is the main component of Lewy bodies formed in midbrain dopaminergic neurons which is a pathological characteristic of Parkinson's disease. It has been recently showed to induce endoplasmic reticulum (ER) stress and impair ER functions. However, the mechanism of how ER respon...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Springer Netherlands
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3082648/ https://ncbi.nlm.nih.gov/pubmed/19960284 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12192-009-0157-2 |
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