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The b′ domain of protein disulfide isomerase cooperates with the a and a′ domains to functionally interact with platelets

BACKGROUND: Protein disulfide isomerase (PDI) is an oxidoreductase consisting of four domains arranged in the order of a-b-b′-a′ with an x-linker between the b′ and a′ domains. PDI binds to the αIIbβ3 integrin on activated platelets, and potentiates activation of this integrin through the C-terminal...

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Détails bibliographiques
Publié dans:J Thromb Haemost
Auteurs principaux: Wang, Lu, Zhou, Junsong, Wang, Lei, Wang, Chih-chen, Essex, David W.
Format: Artigo
Langue:Inglês
Publié: 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6368866/
https://ncbi.nlm.nih.gov/pubmed/30566278
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jth.14366
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