Fibril growth and seeding capacity play key roles in α-synuclein-mediated apoptotic cell death

The role of extracellular α-synuclein (α-syn) in the initiation and the spreading of neurodegeneration in Parkinson's disease (PD) has been studied extensively over the past 10 years. However, the nature of the α-syn toxic species and the molecular mechanisms by which they may contribute to neu...

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Bibliografiska uppgifter
I publikationen:Cell Death Differ
Huvudupphovsmän: Mahul-Mellier, A-L, Vercruysse, F, Maco, B, Ait-Bouziad, N, De Roo, M, Muller, D, Lashuel, H A
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group 2015
Ämnen:
Original Paper
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4816119/
https://ncbi.nlm.nih.gov/pubmed/26138444
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2015.79
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