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Discovery and characterization of stable and toxic Tau/phospholipid oligomeric complexes

The microtubule-associated protein Tau plays a central role in the pathogenesis of Alzheimer’s disease. Although Tau interaction with membranes is thought to affect some of its physiological functions and its aggregation properties, the sequence determinants and the structural and functional consequ...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Nat Commun
Päätekijät: Ait-Bouziad, Nadine, Lv, Guohua, Mahul-Mellier, Anne-Laure, Xiao, Shifeng, Zorludemir, Gizem, Eliezer, David, Walz, Thomas, Lashuel, Hilal A.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Publishing Group UK 2017
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5698329/
https://ncbi.nlm.nih.gov/pubmed/29162800
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-01575-4
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