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Discovery and characterization of stable and toxic Tau/phospholipid oligomeric complexes

The microtubule-associated protein Tau plays a central role in the pathogenesis of Alzheimer’s disease. Although Tau interaction with membranes is thought to affect some of its physiological functions and its aggregation properties, the sequence determinants and the structural and functional consequ...

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書目詳細資料
發表在:Nat Commun
Main Authors: Ait-Bouziad, Nadine, Lv, Guohua, Mahul-Mellier, Anne-Laure, Xiao, Shifeng, Zorludemir, Gizem, Eliezer, David, Walz, Thomas, Lashuel, Hilal A.
格式: Artigo
語言:Inglês
出版: Nature Publishing Group UK 2017
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5698329/
https://ncbi.nlm.nih.gov/pubmed/29162800
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-01575-4
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