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Discovery and characterization of stable and toxic Tau/phospholipid oligomeric complexes

The microtubule-associated protein Tau plays a central role in the pathogenesis of Alzheimer’s disease. Although Tau interaction with membranes is thought to affect some of its physiological functions and its aggregation properties, the sequence determinants and the structural and functional consequ...

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Detalhes bibliográficos
Publicado no:Nat Commun
Principais autores: Ait-Bouziad, Nadine, Lv, Guohua, Mahul-Mellier, Anne-Laure, Xiao, Shifeng, Zorludemir, Gizem, Eliezer, David, Walz, Thomas, Lashuel, Hilal A.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5698329/
https://ncbi.nlm.nih.gov/pubmed/29162800
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-01575-4
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