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Discovery and characterization of stable and toxic Tau/phospholipid oligomeric complexes
The microtubule-associated protein Tau plays a central role in the pathogenesis of Alzheimer’s disease. Although Tau interaction with membranes is thought to affect some of its physiological functions and its aggregation properties, the sequence determinants and the structural and functional consequ...
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| Опубликовано в: : | Nat Commun |
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| Главные авторы: | , , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Nature Publishing Group UK
2017
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5698329/ https://ncbi.nlm.nih.gov/pubmed/29162800 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-01575-4 |
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