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Complement Regulatory Protein Factor H Is a Soluble Prion Receptor That Potentiates Peripheral Prion Pathogenesis
Several Complement proteins exacerbate prion disease, including C3, C1q, and CD21/35. These proteins of the Complement cascade likely increase uptake, trafficking, and retention of prions in the lymphoreticular system, hallmark sites of early prion propagation. Complement regulatory protein Factor H...
Shranjeno v:
| izdano v: | J Immunol |
|---|---|
| Main Authors: | , , , , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2017
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5698161/ https://ncbi.nlm.nih.gov/pubmed/29070671 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1701100 |
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