Complement Regulatory Protein Factor H Is a Soluble Prion Receptor That Potentiates Peripheral Prion Pathogenesis

Several Complement proteins exacerbate prion disease, including C3, C1q, and CD21/35. These proteins of the Complement cascade likely increase uptake, trafficking, and retention of prions in the lymphoreticular system, hallmark sites of early prion propagation. Complement regulatory protein Factor H...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Immunol
Prif Awduron: Kane, Sarah J, Farley, Taylor K, Gordon, Elizabeth O, Estep, Joshua, Bender, Heather R, Moreno, Julie A, Bartz, Jason, Telling, Glenn C, Pickering, Matthew C, Zabel, Mark D
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2017
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5698161/
https://ncbi.nlm.nih.gov/pubmed/29070671
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1701100
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