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Complement protein C3 exacerbates prion disease in a mouse model of chronic wasting disease
Accumulating evidence shows a critical role of the complement system in facilitating attachment of prions to both B cells and follicular dendritic cells and assisting in prion replication. Complement activation intensifies disease in prion-infected animals, and elimination of complement components i...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3900863/ https://ncbi.nlm.nih.gov/pubmed/24038599 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/intimm/dxt034 |
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