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Fast and sensitive HPLC-MS/MS method for direct quantification of intracellular deoxyribonucleoside triphosphates from tissue and cells

Deoxyribonucleoside triphosphates (dNTPs) are used in DNA synthesis and repair. Even slight imbalances can have adverse biological effects. This study validates a fast and sensitive HPLC-MS/MS method for direct quantification of intracellular dNTPs from tissue. Equal volumes of methanol and water we...

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Detalhes bibliográficos
Publicado no:J Chromatogr B Analyt Technol Biomed Life Sci
Main Authors: Olafsson, Sigurast, Whittington, Dale, Murray, Jason, Regnier, Michael, Moussavi-Harami, Farid
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5698104/
https://ncbi.nlm.nih.gov/pubmed/29032043
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jchromb.2017.10.008
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