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2-Deoxy adenosine triphosphate improves contraction in human end-stage heart failure
We are developing a novel treatment for heart failure by increasing myocardial 2 deoxy-ATP (dATP). Our studies in rodent models have shown that substitution of dATP for adenosine triphosphate (ATP) as the energy substrate in vitro or elevation of dATP in vivo increases myocardial contraction and tha...
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| Pubblicato in: | J Mol Cell Cardiol |
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| Autori principali: | , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2014
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4301986/ https://ncbi.nlm.nih.gov/pubmed/25498214 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2014.12.002 |
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