Interference with Gsα-Coupled Receptor Signaling in Renin-Producing Cells Leads to Renal Endothelial Damage

Intracellular cAMP, the production of which is catalyzed by the α-subunit of the stimulatory G protein (Gsα), controls renin synthesis and release by juxtaglomerular (JG) cells of the kidney, but may also have relevance for the physiologic integrity of the kidney. To investigate this possibility, we...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Am Soc Nephrol
Egile Nagusiak: Lachmann, Peter, Hickmann, Linda, Steglich, Anne, Al-Mekhlafi, Moath, Gerlach, Michael, Jetschin, Niels, Jahn, Steffen, Hamann, Brigitte, Wnuk, Monika, Madsen, Kirsten, Djonov, Valentin, Chen, Min, Weinstein, Lee S., Hohenstein, Bernd, Hugo, Christian P.M., Todorov, Vladimir T.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society of Nephrology 2017
Gaiak:
Basic Research
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5698073/
https://ncbi.nlm.nih.gov/pubmed/28775003
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2017020173
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