Stimulation of Renin Secretion by Angiotensin II Blockade is Gsα-Dependent

Angiotensin II converting enzyme inhibitors (ACEI) or angiotensin II receptor blockers (ARB) presumably stimulate renin secretion by interrupting angiotensin II feedback inhibition. The increase in cytosolic calcium caused by activation of Gq-coupled AT1 receptors may mediate the renin-inhibitory ef...

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Autori principali: Chen, Limeng, Kim, Soo Mi, Eisner, Christoph, Oppermann, Mona, Huang, Yuning, Mizel, Diane, Li, Lingli, Chen, Min, Sequeira Lopez, Maria Luisa, Weinstein, Lee S., Gomez, Roberto A., Schnermann, Jurgen, Briggs, Josephine P.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society of Nephrology 2010
Soggetti:
Basic Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2900955/
https://ncbi.nlm.nih.gov/pubmed/20395378
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2009030307
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