Interference with Gsα-Coupled Receptor Signaling in Renin-Producing Cells Leads to Renal Endothelial Damage

Intracellular cAMP, the production of which is catalyzed by the α-subunit of the stimulatory G protein (Gsα), controls renin synthesis and release by juxtaglomerular (JG) cells of the kidney, but may also have relevance for the physiologic integrity of the kidney. To investigate this possibility, we...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:J Am Soc Nephrol
Main Authors: Lachmann, Peter, Hickmann, Linda, Steglich, Anne, Al-Mekhlafi, Moath, Gerlach, Michael, Jetschin, Niels, Jahn, Steffen, Hamann, Brigitte, Wnuk, Monika, Madsen, Kirsten, Djonov, Valentin, Chen, Min, Weinstein, Lee S., Hohenstein, Bernd, Hugo, Christian P.M., Todorov, Vladimir T.
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society of Nephrology 2017
נושאים:
Basic Research
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC5698073/
https://ncbi.nlm.nih.gov/pubmed/28775003
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2017020173
תגים: הוספת תג
אין תגיות, היה/י הראשונ/ה לתייג את הרשומה!

פריטים דומים