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Generation and characterization of aptamers targeting factor XIa
BACKGROUND: The plasma protease factor XIa (FXIa) has become a target of interest for therapeutics designed to prevent or treat thrombotic disorders. METHODS: We used a solution-based, directed evolution approach called systematic evolution of ligands by exponential enrichment (SELEX) to isolate RNA...
Gardado en:
| Publicado en: | Thromb Res |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2017
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5697752/ https://ncbi.nlm.nih.gov/pubmed/28644959 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.thromres.2017.06.015 |
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