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Characterization of Novel Forms of Coagulation Factor XIa: INDEPENDENCE OF FACTOR XIa SUBUNITS IN FACTOR IX ACTIVATION

Factor XI is the zymogen of a dimeric plasma protease, factor XIa, with two active sites. In solution, and during contact activation in plasma, conversion of factor XI to factor XIa proceeds through an intermediate with one active site (1/2-FXIa). Factor XIa and 1/2-FXIa activate the substrate facto...

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Detaylı Bibliyografya
Asıl Yazarlar: Smith, Stephen B., Verhamme, Ingrid M., Sun, Mao-fu, Bock, Paul E., Gailani, David
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2008
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2633474/
https://ncbi.nlm.nih.gov/pubmed/18192270
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M707234200
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