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Characterization of Novel Forms of Coagulation Factor XIa: INDEPENDENCE OF FACTOR XIa SUBUNITS IN FACTOR IX ACTIVATION

Factor XI is the zymogen of a dimeric plasma protease, factor XIa, with two active sites. In solution, and during contact activation in plasma, conversion of factor XI to factor XIa proceeds through an intermediate with one active site (1/2-FXIa). Factor XIa and 1/2-FXIa activate the substrate facto...

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書誌詳細
主要な著者: Smith, Stephen B., Verhamme, Ingrid M., Sun, Mao-fu, Bock, Paul E., Gailani, David
フォーマット: Artigo
言語:Inglês
出版事項: 2008
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2633474/
https://ncbi.nlm.nih.gov/pubmed/18192270
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M707234200
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