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Exosite-mediated Substrate Recognition of Factor IX by Factor Xia: THE FACTOR XIa HEAVY CHAIN IS REQUIRED FOR INITIAL RECOGNITION OF FACTOR IX
Studies of the mechanisms of blood coagulation zymogen activation demonstrate that exosites (sites on the activating complex distinct from the protease active site) play key roles in macromolecular substrate recognition. We investigated the importance of exosite interactions in recognition of factor...
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| Auteurs principaux: | , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2005
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2292466/ https://ncbi.nlm.nih.gov/pubmed/15829482 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M500894200 |
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