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Exosite-mediated Substrate Recognition of Factor IX by Factor Xia: THE FACTOR XIa HEAVY CHAIN IS REQUIRED FOR INITIAL RECOGNITION OF FACTOR IX

Studies of the mechanisms of blood coagulation zymogen activation demonstrate that exosites (sites on the activating complex distinct from the protease active site) play key roles in macromolecular substrate recognition. We investigated the importance of exosite interactions in recognition of factor...

詳細記述

保存先:
書誌詳細
主要な著者: Ogawa, Taketoshi, Verhamme, Ingrid M., Sun, Mao-Fu, Bock, Paul E., Gailani, David
フォーマット: Artigo
言語:Inglês
出版事項: 2005
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2292466/
https://ncbi.nlm.nih.gov/pubmed/15829482
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M500894200
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