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The Mechanism Underlying Activation of Factor IX by Factor XIa
Factor XI (fXI) is the zymogen of a plasma protease, factor XIa (fXIa), that contributes to thrombin generation during blood coagulation by proteolytic conversion of factor IX (fIX) to factor IXaβ (fIXaβ). There is considerable interest in fXIa as a therapeutic target because it contributes to throm...
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| Glavni autori: | , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2014
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4017667/ https://ncbi.nlm.nih.gov/pubmed/24759143 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.thromres.2014.03.020 |
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