Pediatric Cytochrome P450 Activity Alterations in Nonalcoholic Steatohepatitis

Variable drug responses depend on individual variation in the activity of drug-metabolizing enzymes, including cytochrome P450 enzymes (CYP). As the most common chronic liver disease in children and adults, nonalcoholic steatohepatitis (NASH) has been identified as a source of significant interindiv...

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Bibliografske podrobnosti
izdano v:Drug Metab Dispos
Main Authors: Li, Hui, Canet, Mark J., Clarke, John D., Billheimer, Dean, Xanthakos, Stavra A., Lavine, Joel E., Erickson, Robert P., Cherrington, Nathan J.
Format: Artigo
Jezik:Inglês
Izdano: The American Society for Pharmacology and Experimental Therapeutics 2017
Teme:
Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5697442/
https://ncbi.nlm.nih.gov/pubmed/28986475
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/dmd.117.077644
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