Altered Regulation of Hepatic Efflux Transporters Disrupts Acetaminophen Disposition in Pediatric Nonalcoholic Steatohepatitis

Nonalcoholic fatty liver disease (NAFLD) is the most common chronic liver disease, representing a spectrum of liver pathologies that include simple hepatic steatosis and the more advanced nonalcoholic steatohepatitis (NASH). The current study was conducted to determine whether pediatric NASH also re...

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Vydáno v:Drug Metab Dispos
Hlavní autoři: Canet, Mark J., Merrell, Matthew D., Hardwick, Rhiannon N., Bataille, Amy M., Campion, Sarah N., Ferreira, Daniel W., Xanthakos, Stavra A., Manautou, Jose E., Hesham A-Kader, H., Erickson, Robert P., Cherrington, Nathan J.
Médium: Artigo
Jazyk:Inglês
Vydáno: The American Society for Pharmacology and Experimental Therapeutics 2015
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4429682/
https://ncbi.nlm.nih.gov/pubmed/25788542
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/dmd.114.062703
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