Metabolite signatures of doxorubicin induced toxicity in human induced pluripotent stem cell-derived cardiomyocytes

Drug-induced off-target cardiotoxicity, particularly following anti-cancer therapy, is a major concern in new drug discovery and development. To ensure patient safety and efficient pharmaceutical drug development, there is an urgent need to develop more predictive cell model systems and distinct tox...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Amino Acids
Päätekijät: Chaudhari, Umesh, Ellis, James K., Wagh, Vilas, Nemade, Harshal, Hescheler, Jürgen, Keun, Hector C., Sachinidis, Agapios
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Springer Vienna 2017
Aiheet:
Original Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5696498/
https://ncbi.nlm.nih.gov/pubmed/28421296
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00726-017-2419-0
Tagit: Lisää tagi
Ei tageja, Lisää ensimmäinen tagi!

Samankaltaisia teoksia