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Structural basis for the assembly of the Ragulator-Rag GTPase complex
The mechanistic target of rapamycin complex 1 (mTORC1) plays a central role in regulating cell growth and metabolism by responding to cellular nutrient conditions. The activity of mTORC1 is controlled by Rag GTPases, which are anchored to lysosomes via Ragulator, a pentameric protein complex consist...
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| Izdano u: | Nat Commun |
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| Glavni autori: | , , , , , , , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Nature Publishing Group UK
2017
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5696360/ https://ncbi.nlm.nih.gov/pubmed/29158492 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-01762-3 |
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