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The Rag GTPase-Ragulator complex attenuates TOR complex 1 signaling in fission yeast
Target of rapamycin complex 1 (TORC1) is an evolutionarily conserved protein kinase complex, whose activation in response to nutrients suppresses autophagy. In mammalian cells, amino-acid stimuli induce lysosomal translocation and activation of MTORC1 through the RRAG GTPase heterodimer, which is te...
Tallennettuna:
| Julkaisussa: | Autophagy |
|---|---|
| Päätekijät: | , |
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
Taylor & Francis
2018
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6103401/ https://ncbi.nlm.nih.gov/pubmed/29799770 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2018.1444313 |
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