Wird geladen...
PTEN Regulates Glucose Transporter Recycling by Impairing SNX27 Retromer Assembly
The tumor suppressor PTEN executes cellular functions predominantly through its phosphatase activity. Here we identified a phosphatase-independent role for PTEN during vesicular trafficking of the glucose transporter GLUT1. PTEN physically interacts with SNX27, a component of the retromer complex th...
Gespeichert in:
| Veröffentlicht in: | Cell Rep |
|---|---|
| Hauptverfasser: | , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Cell Press
2017
|
| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5695913/ https://ncbi.nlm.nih.gov/pubmed/29117568 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2017.10.053 |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|