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PTEN modulates EGFR late endocytic trafficking and degradation by dephosphorylating Rab7
Tumour suppressor phosphatase and tensin homologue deleted on chromosome 10 (PTEN) is a lipid phosphatase that negatively regulates growth factor-induced survival signalling. Here, we demonstrate that PTEN attenuates epidermal growth factor receptor (EGFR) signalling by promoting late endosome matur...
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| Pubblicato in: | Nat Commun |
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| Autori principali: | , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Nature Publishing Group
2016
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4754336/ https://ncbi.nlm.nih.gov/pubmed/26869029 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms10689 |
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