Chargement en cours...

Late endosomal Rab7 regulates lysosomal trafficking of endocytic but not biosynthetic cargo in Trypanosoma brucei

We present the first functional analysis of the small GTPase, TbRab7, in Trypanosoma brucei. TbRab7 defines discrete late endosomes closely juxtaposed to the terminal p67(+) lysosome. RNAi indicates that TbRab7 is essential in bloodstream trypanosomes. Initial rates of endocytosis were unaffected, b...

Description complète

Enregistré dans:
Détails bibliographiques
Publié dans:Mol Microbiol
Auteurs principaux: Silverman, Jason S., Schwartz, Kevin J., Hajduk, Stephen L., Bangs, James D.
Format: Artigo
Langue:Inglês
Publié: 2011
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4324464/
https://ncbi.nlm.nih.gov/pubmed/21923766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2958.2011.07842.x
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!