A global analysis of SNX27-retromer assembly and cargo specificity reveals a function in glucose and metal ion transport

The PDZ domain-containing sorting nexin 27 (SNX27) promotes recycling of internalized transmembrane proteins from endosomes to the plasma membrane by linking PDZ-dependent cargo recognition to retromer-mediated transport. Here, we employed quantitative proteomics of the SNX27 interactome alongside q...

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Bibliografiske detaljer
Main Authors: Steinberg, Florian, Gallon, Matthew, Winfield, Mark, Thomas, Elaine, Bell, Amanda J., Heesom, Kate J, Tavaré, Jeremy M., Cullen, Peter J.
Format: Artigo
Sprog:Inglês
Udgivet: 2013
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4052425/
https://ncbi.nlm.nih.gov/pubmed/23563491
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb2721
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