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Biochemical and biophysical methods for analysis of Poly (ADP-Ribose) Polymerase 1 and its interactions with chromatin
Poly (ADP-Ribose) Polymerase I (PARP-1) is a first responder to DNA damage repair and participates in the regulation of gene expression. The interaction of PARP-1 with chromatin and DNA is complex and involves at least two different modes of interaction. In its enzymatically inactive state, PARP-1 b...
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| Publié dans: | Methods Mol Biol |
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| Auteurs principaux: | , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2017
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5695667/ https://ncbi.nlm.nih.gov/pubmed/28695514 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-4939-6993-7_16 |
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