Biochemical and biophysical methods for analysis of Poly (ADP-Ribose) Polymerase 1 and its interactions with chromatin

Poly (ADP-Ribose) Polymerase I (PARP-1) is a first responder to DNA damage repair and participates in the regulation of gene expression. The interaction of PARP-1 with chromatin and DNA is complex and involves at least two different modes of interaction. In its enzymatically inactive state, PARP-1 b...

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Vydáno v:Methods Mol Biol
Hlavní autoři: Chassé, Maggie H, Muthurajan, Uma M, Clark, Nicholas J, Kramer, Michael A, Chakravarthy, Srinivas, Irving, Thomas, Luger, Karolin
Médium: Artigo
Jazyk:Inglês
Vydáno: 2017
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5695667/
https://ncbi.nlm.nih.gov/pubmed/28695514
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-4939-6993-7_16
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