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Interspecies Comparative Genomics Identifies Optimal Mouse Models of Systemic Sclerosis

OBJECTIVE: Understanding the pathogenesis of systemic sclerosis (SSc) is confounded by considerable disease heterogeneity. Animal models of SSc that recapitulate distinct subsets of disease at the molecular level have not been delineated. We applied interspecies comparative analysis of genomic data...

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Detalhes bibliográficos
Publicado no:Arthritis Rheumatol
Main Authors: Sargent, Jennifer L., Li, Zhenghui, Aliprantis, Antonios O., Greenblatt, Matthew, Lemaire, Raphael, Wu, Ming-hua, Wei, Jun, Taroni, Jaclyn, Harris, Adam, Long, Kristen B., Burgwin, Chelsea, Artlett, Carol M., Blankenhorn, Elizabeth P., Lafyatis, Robert, Varga, John, Clark, Stephen H., Whitfield, Michael L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5695038/
https://ncbi.nlm.nih.gov/pubmed/26945694
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.39658
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